If put on a platform, as I think PKAY is suggesting, then there is no field rotation. But they are good only for short, say 30 second to one minute exposures. So you end up stacking hundreds of frames to get the exposure time needed. Or your use track and accumulate. Problem with T&A is that it includes good and bad frames and often uses less than optimal flats and darks.
So yes it can be done but a good EQ mount will serve you better for deep sky.

For planetary photography either a platform or a dob driven on both axes would work quite well. Field rotation is not an issue and a slight drift will actually help resolution if the images are "drizzle" processed.

Also, if deep sky is your interest and you've never done it before, start with something a lot smaller and with a much shorter focal length than a typical 12" dob tube. You are facing a much steeper learning curve with a big scope. The shots you can get with a small scope will amaze you. Being that a typical location results in 3" stars even a 4" scope has as much resolution as a 12". Longer exposure compensates for aperture quite well. The mount needed is far cheaper and easier to control as well.

But if planetary imaging is your interest your idea should work quite well.

Rick