Well, while it's fun to "Down in Flames" the Star Trek universe, it might be too late to do so. TNG has replicators and holodecks, and TOS had sentient androids. There is no real reason for anyone in the federation to do a lick of work--they could spend all their time in a holofantasy.

Replicators can reproduce matter down to proteins (if they couldn't, replicated food would be either non-nutritious or poisonous). Replicators can reproduce phasers. There's no real reason (other than technology police) why replicators can't reproduce living matter, replicators, holodecks, androids, or starships. Now, maybe the Federation is controlling the technology just so the Federation doesn't degenerate to the point where a visiting delegation from the Duchy of Grand Fenwick can't single-handedly conquer the Federation, but any rebel cause isn't going to feel so constrained. They'll pull the governors off the replicator and start building up their own fleet. But one of the technicians is bound to dup a couple extra holodecks (just to check things out) and *poof* your rebels are off playing badminton with the holofloozies.

The Federation now has mind control technology (from The Game); they've probably had it for a while, most likely the holoprojections are filled with subliminal messages (WORK IS GOOD, THINKING IS EVIL, FEMALE ALIENS SHOULD WEAR CATSUITS, THIS IS ONLY A GAME, OBEY AUTHORITY, IT'S PERFECTLY ACCEPTABLE FOR ENSIGNS TO BE ON THE SENIOR STAFF). The rebels might choose to edit these; if they leave any in they're sliding down a slippery slope.

Maybe it would be better to have everything from the third season of TOS be one of McCoy's cordrazine nightmares.