A proficient, continually expanding, technical competence is the key, and humans have it to varying degrees. I expect that we will find it throughout the MW.

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For those inclined to oppose human meddling with the structure of the universe or the composition and configuration of objects and groups of objects within the universe, consider:
Whether there is a limit to the magnitude of a modulation of chaos below which order remains invariant? Or, is order but a fiction invented by perspectives applied over finite, however large, time intervals?