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Quote:
Originally Posted by antoniseb
I'm not sure we know whether the stay in 0.4g Martian gravity would result in calcium loss in the bones.
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Calcium in healthy interior bone is in constant turnover. It is pulled out into the blood for metabolic functions and redeposited where called for. An important signal for deposition is damage to the bone.
Physical stress to bones increases deposition over time and increases bone strength as seen in those engaging in athletic activity. Normally active adults are able to just keep their bone density. A lack of bone stress due to reduced gravity will definately lower bone density over time. This is a fairly slow process to be sure but would effect anyone in low gravity for years.