Let's forget most of the labels a moment.


And stick with just two basic labels.

Sane
and
Insane.


I am presenting my "opinion" and not anything strictly scientific:

I'll give my own definition:
To be sane means to follow the most rational course using critical thinking.
To be insane is to follow irrational course and defy reality.

A lot of people do not realize how insane they are, in even every day aspects.
We're all evolved to be insane. Insanity has allowed us better chances of survival.
But with our broadening intellect, insanity also became a disadvantage to technological progress and expanding sciences.
However, it remains an advantage when it comes to breeding.