To be sure, clint, but the discovery of Life beyond Earth, whether microbial or intelligent, raises a whole host of other questions about who we are, why we're here, what we're to do ... our place in the cosmos, fundamentally changing our perspective.
Into the 21st century there remain multitudes who think Earth and Mankind upon it are special, unique in some way. I think to discover otherwise will be most profound for religion, and if ETi, for science.

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"Where the telescope ends, the microscope begins. Which of the two has the greater view?" - Hugo

"Men occasionally stumble over the truth, but most pick themselves up and hurry off as if nothing had happened." - Churchill