I like the one from Apollo 10 after separation of LM and CSM, when Stafford or Cernan asked Young: "Have a good time while we're gone, Babe...and don't get lonesome out there, John. And don't accept any TEI (trans Earth injection) updates."

Young: "Don't you worry, until you get back, I ain't copying any more pads."

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"Flying in space is risky business, but just staying on this planet is risky business too." - John Young, astronaut