Originally Posted by JohnD

For a start, doesn't quantum theory say that we cannot know everything about everything? That discounts determinism, which late in the 19th Century led many to predict, like you, the end of endeavour.
The 'Scientific method' thread will show you that it is a constant process of refinement, interspersed with leaps onto new planes. Our most recent was relativity, but we (humans, possibly not you or me) will see more.