Perhaps this is true. For instance, I do not know if there is a murderer outside my home at this moment. I am comfortable, because I see it as very unlikely. Some (very few I think) may be pulverized by such uncertainty to a greater or lesser degree and refuse to leave the house alone or unarmed or any other "paranoid' reasons.

This is certainly different than the mindset concept of uncertainty and its metaphysical implications, but there is a common concept of uncertainty.